Class setup, material covered by exams, cell theory, cancer

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Life Science
LIFE 210
Paul Laybourn

22 August Tutorials On RamCT Quicktime movies (course content > learning modules) Lecture objective Key terms and concepts, course ‘content’ Notes version of slides (pdf) Additional movies and links Quizzes Taken on RamCT Practice multiple choice questions to emphasize key points, review course content Additional Study Questions Download from RamCT (Course Content > Learning Modules) Help prepare you for essay questions on exams Will post answers a few days later Suggest practicing writing out the answers (diagrams) Keyword Glossaries are optional iClicker Questions in Class Register your iClicker Promote critical thinking in cell biology Lectures Covered by Five Exams Exam 1 will cover the material in lectures 1 – 9 The chemical components of cells, chemical properties, and protein structure and function: The molecules that make up a cell and their chemistry Chemical bonds and interactions Biological order and energetics Molecular recognition Protein structure and folding Proteins as catalysts and enzyme regulation Exam 2 will cover the material in lectures 10 – 17 Membrane structure and function: Membrane lipid structure and function Lipid bilayers and their properties Membrane protein structure and function Transport across membranes Cellular compartmentalization Protein trafficking between cellular compartments ER, Golgi, and membrane processing and trafficking Endocytosis Exam 3 will cover the material in lectures 18 – 25 Metabolism: Catabolism and anabolism; metabolic pathways Metabolic regulation Electron transport and oxidative phosphorylation in mitochondria Electron transport and oxidative phosphorylation in chloroplasts Exam 4 will cover the material in lectures 26 – 33 Cellular communication: Signaling systems and their mechanisms Cytoskeleton: Filament types, composition, and function Motor proteins Cytoskeleton dynamics Exam 5 will cover the material in lectures 34 – 40 More on cell shape and movement and cellular growth control Cytoskeleton in cellular behavior Cell cycle and its control and regulation Programmed cell death (apoptosis) and senescence Cell biology of cancer What is Life? 1. Reproduction 2. Flow of matter and energy – metabolism 3. Adaptation 4. Organization Membranes “Emergent properties” – context is as important or more important thatn the parts Cell Theory – Cells Are the Basic Unit of All Life 1665 Robert Hooke “Cellulae” little rooms in cork 1670 Anton van Leeuwenhoek Improved microscopes to look at live cells 1830s Better microscopes 1838 Robert Brown Cell “kernel” or nucleus 1839 Theodor Schwann & Matthias Schleiden “Cell theory” All organisms are cells or are made up of cells Cells are the most basic unit of life 1858 Rudolfe Virchow All cells arise from another cell 1937 E. Chatton
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