[MIP 342] - Midterm Exam Guide - Ultimate 27 pages long Study Guide!
5 Oct 2016
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2ndary immune response: previously seen pathogen attacks again, ab already there from first time, memory b and t cells from first exposure recognize pathogen and proliferate rapidly, attack is usually quickly rejected. Ab response made by b cells- but paralleled by cd4 and cd8 t cells. Lag phase for antigen a when dendritic cells gather antigens and bring them to b and t cells in ln. Lasts for a while but decreases slightly after a few weeks. Since flu has some variation, will be exposed to new b antigen on the virus and will start primary immune response to that antigen again with lag phase. Immature dendritic cells have macropinosomes large vacuoles to drink up antigen particles. Mature dendritic cells then travel through lymphatic tissue via afferent lymphatic vessels drain into ln. Present antigens to na ve but mature b cells and t cells in. Freshmen b and t cells travel to node via high endothelial venules.
