PHI-2635 Study Guide - Midterm Guide: Cotton Swab, Venereal Disease Research Laboratory Test, Chancroid

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6 Oct 2016
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The following questions come from the reading and lecture on the guatemala std inoculation. Be able to describe the serology and std arms of the study. 4 specific tests: kahn, mazzini, kolmer, vdrl slide tests. Blood samples and lumbar punctures were periodically taken and subjected to one or more syphilis testing methods to indicate if the blood contained antibodies against syphilis. If there were antibodies, it was concluded that the person either has an active form of syphilis or previously had it. Guatemala offered more opportunities than in the u. s. and weren"t going to hurt any post-war us citizens. Syphilis may be dependent on breaks in the mucous membrane of the penis and if the inoculation destroyed the membrane, they could offer a more physiological approach to the problem. Importance of the study and their responsibility to the patients. Minors, prisoners, and those with impaired decision making. Prisoners, conscripted soldiers, institutionalized psychiatric patients, children.

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