BISC 3754- Midterm Exam Guide - Comprehensive Notes for the exam ( 33 pages long!)
16 Feb 2018
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Document Summary
Rna processing: introns removed, 5" cap, poly a tail. Dna: deoxy ribose sugar (2" lacks oh), nitrogenous base attached to 1" carbon, phosphate group attached to 5" carbon. Gc pair had 3 hydrogen bond (more stable), at pair has 2 hydrogen bonds. 5" end always has a free phosphate group and 3" has free oh group. Sugar-phosphate backbone on outside, bases on inside. Two strands are joined by hydrogen bonds between complementary bases. Major and minor grooves in helix- many enzymes & proteins bind to the major groove. Ribose sugar (2" and 3" oh groups) U (pyrimidine) pairs with a (2 hydrogen bonds) Usually single stranded but can become double stranded if it complementary base pairs. 3d structure is stabilized by hydrogen bonds and non covalent interactions between nucleotides. Genetic code is redundant= each amino acid can have more than one codon. There are 20 amino acids and 64 possible codons trna.
