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1. The histones that form the core of the nucleosome get into the nucleus by which of the following?
a) Passive diffusion through nuclear pores
b) Selective and facilitated active transport through nuclear pores
c) Ribosomes located in the nucleus synthetize histones in the nucleus
d) Histones are made at the ER membrane and then diffuse to the nucleus
2. Membrane proteins that belong to the golgi, lysosome, or plasma membrane first pass through which organelle before reaching their final subcellular destination?
a) The golgi apparatus
b) The smooth ER
c) The nucleus
d) The ER membrane
e) The ER lumen
3. Where in the cell would a ribosomal protein be located if it has had its nuclear export signal inactivated (non-functional or non-existent).
a) The protein would be found in the ER lumen
b) The protein would remain in the nucleus
c) The protein would be secreted
d) The protein would remain in the cytoplasm
e) The protein would be in the ER membrane
4. Where would be the final destination of a protein if it contained a NLS anywhere in the protein sequence (and which is exposed to the cytoplasm after protein folding) but also contained an ER signal sequence at the carboxy terminus?
a) The ER lumen
b) The nucleus
c) The cytoplasm
d) The inner nuclear membrane
e) The ER membrane
5. The sequence K-D-E-L serves as a retention/retrieval signal for ER proteins.
6. The following are true for both cell membrane proteins and secretory proteins EXCEPT?
a) Precursors of the mature proteins contain signal sequence.
b) Both types of proteins contain stop-transfer sequences
c) Both types of proteins enter the ER while being synthetized
d) Both types of proteins pas through the golgi apparatus
e) Both are carried by clatherin-coated vesicles
7. If you isolate a regulated secreted protein from a secretory/storage vesicle and inject it into the cytosol, is will?
a) Be secreted through channels in the plasma membrane
b) Be taken up into secretory vesicle and secreted
c) Remain in the cytosol until it is degraded
d) Be taken up into the rough ER and follow the secretory pathway
What step in DNA replication precedes the pairing of complementary bases?
polymerization of DNA.
formation of the histone core.
separation of the two strands.
joining of the two strands.
In eukaryotes, transcription occurs in the
Normal human body cells contain how many chromosomes?
Hershey and Chase performed an experiment in which they used radioactive isotopes to phosphorus and sulfur to label different components of bacterial viruses. Their results clearly showed that
the viruses did not contain protein.
genetic material normally contains radioactive isotopes.
the viruses did not contain DNA.
protein was entering into the infected bacteria.
DNA was entering into the infected bacteria.
A package of histones with DNA wrapped around them forms spherical structures called
does not require proteins.
is constantly happening in a cell.
occurs in G1 of interphase.
takes place in the nucleus of the cell.
occurs in the cytoplasm of the cell.
The two subunits of the ribosome join during
promotion of transcription.
initiation of translation.
termination of transcription.
termination of translation.
DNA replication of a single DNA molecule is referred to as semiconservative because
each of the two DNA molecules will consist of one parental strand and one newly synthesized strand.
all the DNA strands in the two DNA molecules will have both parental and newly synthesized DNA.
it results in two nonidentical DNA molecules.
of the two DNA molecules, one is made up totally of parental DNA, while the other is entirely newly synthesized DNA.
one DNA strand is replicated continuously, while the other must be replicated discontinuously.
The bases are bonded to what part of the backbone of the DNA molecule?
the 4â carbon atom of the sugar molecule.
the 3â carbon atom of the sugar molecule.
the 5â carbon atom of the sugar molecule.
the 1â carbon atom of the sugar molecule.
the 2â carbon atom of the sugar molecule.
Anabolic pathways of metabolism are pathways that:
a. build complex molecules from simple ones.
b. release stored chemical energy.
c. take place primarily in skeletal muscle
d. make large quantities of ATP.
The sum of all chemical reactions in a cell is referred to as _______________.
Organisms that derive both their energy and carbon from organic compounds are:
It is often stated that the phosphate bonds in ATP are "high energy," but in fact, they are not notably high in energy. Rather, they are easy to break, and the âG of hydrolysis is a "useful" quantity of energy. What makes the phosphate bonds easy to break?
a. They are close to the destabilizing nitrogenous base adenosine
b. Positive charges on amino groups repel each other.
c. Negative charges on phosphate groups repel each other
d. High acidity attacks bonds between amino acids.
Which of the following describes ATP hydrolysis? Select all that apply
[mark all correct answers] a. exergonic
c. often coupled to a reaction that has a positive ÎG
Which of the following describes catabolic reactions?
a. They are endergonic and have a negative change in free energy
b. They are exergonic and have a negative change in free energy
c. They are exergonic and have a positive change in free energy.
d. They are endergonic and have a positive change in free energy.
Why are cells not infinitely big?
a. Because they wouldn't fit in an organism
b. Because they would have a small surface area:volume ratio and substances would diffuse in and out too slowly
c. Because they would have a large surface area to volume ratio and substances would diffuse in and out too quickly
How is organelle movement around cells controlled?
a. the nucleus directs the movement of organelles in a cell
b. the cytoskeleton is like a monorail that moves organelles in a cell via motor proteins
c. organelles do not move, they have a fixed position in the cell
d. organelles move by facilitated diffusion in the cell
1. Prokaryotic cells lack:
a. a. A nucleus
c. cell membrane
e. A and B
Rough endoplasmic reticulum (rER)
a. a. Makes cell membranes
b. has ribosomes attached
c. are a site of protein synthesis
d. all of the above
Match the items.
The task is to match the lettered items with the correct numbered items. Appearing below is a list of lettered items. Following that is a list of numbered items. Each numbered item is followed by a drop-down. Select the letter in the drop down that best matches the numbered item with the lettered alternatives.
a. help to digest worn-out or damaged organelles.
b. Takes in molecules in transport vesicles, modifies them, and sends them back out in vesicles
c. makes sugar
d. makes ATP
e. assembles the ribosomes
f. gives the cell structure
g. move material around the cell
3. the golgi apparatus