CHE 110 Study Guide - Midterm Guide: American Cancer Society, National Health Interview Survey, Thrombocytopenia
A Molecule that Rocks My World (Melatonin)
• Chemical Name: N-acetyl-5-methoxy tryptamine
• Molecular Structure: formula is C13H16N2O2
• State at Room Temperature:
• Other Important Chemical Characteristics:
o Bioavailability: 30-50%
o
o Molecular Weight: 232.278g/mol
• Why you chose the molecule:
o I have a hard time sleeping at night, and I researched healthy
ways to help sleeping patterns. None of the options really
helped me, so when I went to my doctor and they prescribed
melatonin to me, I was very hesitant that this would work for
e. I’e ee usig elatoi for si oths o, ad
sleeping habits are extremely better. Melatonin helps me clear
my mind at night, and fall right to sleep, which is amazing.
• How has it changed the world in which we live in? Why should we care
about it? What should we know about it?
o It has also improved blood pressure control in people with
nocturnal hypertension.
o Tentative evidence shows that melatonin may help reduce some
types of headaches including cluster headaches, and is known to
aid in reducing the effects of jet lag.
• Where does it come from? When was it discovered/invented?
o It’s a iogei aie that is foud i aials ad plats. In
aals, it’s produed the pieal glad (a sall glad i the
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Document Summary
When was it discovered/invented: it"s a (cid:271)ioge(cid:374)i(cid:272) a(cid:373)i(cid:374)e that is fou(cid:374)d i(cid:374) a(cid:374)i(cid:373)als a(cid:374)d pla(cid:374)ts. In (cid:373)a(cid:373)(cid:373)als, it"s produ(cid:272)ed (cid:271)(cid:455) the pi(cid:374)eal gla(cid:374)d (a s(cid:373)all gla(cid:374)d i(cid:374) the brain). Secretion increases in darkness and decreases during e(cid:454)posure to light. It"s i(cid:373)pli(cid:272)ated i(cid:374) the regulatio(cid:374) of sleep, (cid:373)ood, a(cid:374)d reprodu(cid:272)tio(cid:374). Should we use it? (dangerous/poisonous: it"s used as a (cid:373)edi(cid:272)atio(cid:374) for i(cid:374)so(cid:373)(cid:374)ia, (cid:271)ut s(cid:272)ie(cid:374)tifi(cid:272) e(cid:448)ide(cid:374)(cid:272)e is i(cid:374)suffi(cid:272)ie(cid:374)t to de(cid:373)o(cid:374)strate a (cid:271)e(cid:374)efit i(cid:374) this area. It can cause nausea, next-day grogginess, and irritability. In the elderly, it can cause reduced blood flow and hypothermia: other important information, individuals with autism spectrum disorders (asd) may have lower than normal levels of melatonin. There is a high demand for sleep aids, especially in the u. s. Interview survey done in 2002, and again in 2007, found 1. 6 million us adults were using complementary and alternative sleep aids for insomnia. Melatonin was a top choice: however melatonin dose more than influence sleep.
