Chapter 23 (98% on the test)

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Louisiana State University
Biological Sciences
BIOL 2051

Chapter 23 Human Microflora and Nonspecific Host Defenses Highly recommended that you read this chapter in the textHuman MicrofloraHumans are colonized by many microbesNormal floracommensal mutualistic organismsMicrobe populations change constantlyVary with type of tissue and conditionspH moisture other microbes presentIntestinal flora varies with food eatenCan cause disease if reach abnormal locationMetagenome is a collective genome of all microbes in and on the bodyNormal Human FloraThere are billions of microbial cells living inon the human bodyAreas which should be sterileInternal organsBloodCerebrospinal fluidSites where bacteria are normally foundSkinOral cavityGastrointestinal tractRespiratory tractUrogenital tractSee Fig 231Human Microflora SkinSkin is difficult to colonizeDry salty acidic protective oils lyzozyme Microbes grow mostly in moist areasunderarms genitals etcAssociated with sebaceous oil glands and apocrine sweat glands pH 46Factors that affect types of normal flora weather age personal hygieneMicrobes commonly associated with the skinMost are G bacteriaStaphylococcusStreptococcusPropionibacterium Gramanaerobic rodsPropionibacterium acnes can cause acneBacillusSome yeastsCandidaHuman Microflora EyeMost inhibited by lysozyme and continual rising of conjunctiva eye surfaceSometimes S epidermidis and some Gram rods can temporarily reside in eye without causing infectionPinkeyeconjunctivitis can be caused by several types of bacteria and viruses
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