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Final

Final Microbiology Exam Chp 25 26 (got 94% in the course)

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Department
Biological Sciences
Course
BIOL 2051
Professor
All Professors
Semester
Winter

Description
Chapter 25 Microbial PathogenesisHostPathogen InteractionsInfectionentry of pathogen or parasiteInfection doesnt always cause diseaseMost infections removed by immune systemPrimary pathogensHave ability to penetrate host defensesOpportunistic pathogensCause disease only in comprised hostsImmune system defectiveBreak in tissue allows organism access to new siteLoss of other microfloraallows organism to bloomPathogenicity of organismMeasure of ability to cause diseaseDetermined by genetic makeup of organismInfectious dose ID50Number of organisms to colonize 50 of hostsVirulenceRate of lethal infectionsLethal doseLD 50Number of organisms to kill 50 of hostsInfection CycleSpread by direct contact Spread by indirect contactContact with fomitesinanimate object or substance that can carry infectious microbesHorizontal transmission via vectors typically insectsMosquitoes Yellow fever malaria Reservoir for disease organism could be a bird bird to mosquito to humanMay not show disease symptomsMode of entry depends on pathogenMucosal surfaces wounds insect bitesVirulence FactorsVirulence genesEncode factors allowing pathogen to invade hostToxins attachment proteins capsulesPathogenicity islandsSection of genomeContain multiple virulence genesOften encode related functionsEg protein secretion system toxin productionTransferred as a block from other organism
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