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Microbiology Test 2 (got 96%)

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Biological Sciences
BIOL 2051
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Chapter 6 Virus Structure and FunctionGeneral Properties of Viruses virionsObligate intracellular parasite made of nucleic acid surrounded by a protein coatOnly replicate inside hostNo nucleus organelles cytoplasmViral genomes containinformation for taking over host cellinformation for making viral proteinsCapsid genome replication proteinsVirus StructureCapsidsCapsid protein coat surrounding nucleic acidCapsid proteins are arranged to give virion symmetry Isohedral capsids poliovirus herpes virusRoughly spherical20 equilateral triangles or facesFilamentous capsids M13microbiology uses Ebolavirus that causes a particular feverLong tube of protein with genome insideTube made up of 100s of identical protein subunitsTube length reflects size of viral genomeComplex capsids Mixture of icosahedralfilamentous shapesMany Bacteriophage viruses that infect bacteriaAssymetrical irregular shapesTend to be larger virusesPoxvirusesVaccinia cowpox virusVirus StructureEnvelopesEnvelope lipid bilayer around capsid of some virusesAllows fusion to host cell membraneOnly occurs if host cell not covered by cell wallBacteriphages are NONenvelopedEnvelope lipids come from hostNot encoded by viral genomeProteins embedded in envelope may be encoded by virusCoats viral capsid as virus leaves cellVirus StructureGenomeDNA or RNAIncludes genes encodingviral proteinsCapsidEnvelope proteins if virus is envelopedAny polymerase not found in host cellInternational Committee on Taxonomy of Viruses classification system based on1 Genome compositionDNA or RNASingle or double strandedLinear or CircularWhole or segmentedClassified by Baltimore method2 Capsid symmetryhelical or icosahedral 3EnvelopePresence or absence of host derived envelope4 Size of virus particleRelated viruses are similar in size5 Host Range Related viruses infect same or related hostsBaltimore virus classification based on genome structureGroup I Double Stranded DNA Herpesvirus groupcold sores venereal disease chicken poxPoxvirus groupsmallpox vaccinia cowpox remain latent in the body for years becoming active Group IISingle stranded ParvovirusGroup III Double straded Rotavirus member of reovirus family most common cause of infant diarrheaGroup IVsense single stranded RNA RNA genome acts directly as mRNA for making proteins West Nile virus hepatitis C poliovirus rhinovirus coldsGroup Vsense single stranded Genomic RNA does not serve directly as mRNA but is transcribed into a complement thay functions as mRNa Often segmentedInfluenza rhabdovirus rabies Ebola measles Group VIRetroviruses
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