BIOL 2160 Study Guide - Midterm Guide: Ligand-Gated Ion Channel, Diabetes Mellitus Type 2, Hyperglycemia

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Too thin because they have chronic high sugar. If sugar is high in blood, its low in cells. So cells must burn protein and fats for energy. Insulin dependent- must inject insulin to control their disease. Producing enough insulin but cells aren"t responding to it. Glucose actually leaves cells when glut 4 is attached to membrane. Once you lose weight and get rid of cellular glucose, you can control your insulin levels. K+ only more permeable at rest bc leak channels are only ones open at rest. (-70) is long ways from +55 so it has to travel further to reach equilibrium potential of na than to reach k. **once ach binds to receptors, cell is no longer at rest. Na channels open and driving force of na is stronger. Once signal starts to hit cell, cell is no longer more permeable to k+ K channels are slow to open, na channels (activation and inactivation gate) both swing open.

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