GN 311 Study Guide - Midterm Guide: Maurice Wilkins, Microrna, Thymine
Document Summary
Joins new dna strands by catalyzing the formation of a phosphodiester bond. Used in dna repair and dna replication. ** dna pol(cid:455)(cid:373)erases ha(cid:448)e to ha(cid:448)e a (cid:1007)" oh to start addi(cid:374)g (cid:374)u(cid:272)leotides to ** When rnase h removes the rna primer (created by primase) from the lagging strand, the polymerase i then fills in the necessary nucleotides between okazaki. Adds nucleotides but does not join them (ligase does this) Formed by the combination of an enzyme with a coenzyme. Primers are important for the beginning of the replication reaction. Enzyme that synthesizes short rna sequences called primers. Creates rna primers on single stranded dna during replication. Over rotated in same direction as dna coil so left-handed supercoil compensates. Dna is underwound so right-handed supercoil compensates. Attaches at replication fork and moves into the fork. Breaks hydrogen bonds as the replication fork moves along the dna. Binds to single stranded dna to stabilize.
