GENE 540 Midterm: DNA Replication Checkpoints
Document Summary
Ongoing dna replication checkpoint this is the checkpoint that is looking for if dna replication is still going on or not before the cell can go into m-phase. If there is ongoing dna replication, this blocks the entry into m-phase. G2 nucleus delays entering m-phase until the s-phase nucleus completes dna synthesis. This most likely means that the s-phase nucleus must send out a signal that prevents the. Prempf it contains the inhibitory phosphate; activempf the inhibitory phosphate is removed. When dna replication is going on, you are producing cyclin b, but while replication is in progress, the ongoing dna replication checkpoint inhibits the mpf (it inhibits the prempf from going to. Active mpf) this step is that removal of that inhibitory phosphate on y-15. The last step on this diagram would be the trigger to go into m- phase (cdc25 removes the inhibitory phosphate from.
