PSIO 532 Study Guide - Final Guide: Proximal Tubule, Inulin

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1 Sep 2018
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Ux * v = (gfr * ax) - rx + sx. For as substance, x, that is freely filtered. Compare excretion rate (ux*v) with filtered load (gfr * ax) if ux*v > gfr * ax, then net tubular secretion occurred. if ux*v < gfr * ax, then net tubular reabsorption occurred. Uxv = excretory rate (the rate at which x is excreted in the urine, units mg/min) Gfr * ax = filtered load (rate at which x is filtered, also amount/time) Rx = reabsorptive rate(rate at which x is reabsorbed, amount/time) Sx = secretory rate(rate at which x is secreted, amount/time) A substance may be filtered only or filtered and reabsorbed or filtered and secreted or filtered, reabsorbed and secreted. Some substances may be metabolized by the kidney as well. The above statements refer only to the net effect of what goes into the nephron and what finally exits by way of the urine.

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