CHM 1430 Study Guide - Final Guide: Elution, Adsorption, Aluminium Oxide
Document Summary
Resonance is activating ring by increasing e-density. e. g. negative charges around the ring. The most nucleophilic parts of the ring are the ortho and para positions (where the negative lies) Resonance is deactivating ring by decreasing e-density. e. g. positive charges around the ring. The most nucleophilic parts are the where the double bonds act as nucleophiles to give up a lone pair, which are the meta positions. Thin layer chromatography (tlc) a separation technique that utilizes the concept of "like dissolves like" to separate the different parts of a mixture. Can vary from very polar (e. g. water, methanol) to much less polar (e. g. Can vary from very polar (e. g. water, methanol) to much less polar (e. g. ligroin) Mixtures of solvents so that we can tailor the relative polarity of the eluent. By changing the ratio of solvents in the eluent mix, we can influence the speed at which compounds will elute through the stationary phase.
