KINES 350 Study Guide - Final Guide: Heart Failure, Foam Cell, Coronary Artery Disease

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Explain why acid-base regulation is important to exercise performance. Outline the principal systems (respiratory and renal) available to regulate acid-base status. The principal systems available to regulate acid-base status are buffering systems, respiratory compensation and renal compensation. Buffering systems are the primary defense, respiratory compensation is the second line of defense, and renal compensation is the third line of defense. Intracellular or muscular buffering systems are made of. 30% bicarbonate (hco3-), 10% phosphates (hpo3-), 60% negatively charged proteins, miscellaneous other compounds such as citrate. Extracellular or blood buffering systems are made of 65% bicarbonate, 29% phosphates, 5% negatively charged proteins and 1% hemoglobin. Respiratory compensation is the rapid excretion of h+ via carbonic acid. In pulmonary ventilation, the increase in h+ ions stimulates an increase in ventilation. This leads to a decrease in co2 in the blood plasma, and the buffering of h+ causes an increase in co2 formation.

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