BIOL 53700- Midterm Exam Guide - Comprehensive Notes for the exam ( 58 pages long!)

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The immune system is very important and is involved in infections, vaccines, cancer, transfusions/transplantations, autoimmunity, and allergy. Difficult because everyone"s bodies are different and this means so will there therapy and treatment of disease. Immunology- study of the body"s defense against infection. Roles of immune system: maintain homeostatic tissue functions, fight pathogens, repair tissue injury, tolerate commensal microbiome. Pathogen- an organism that can induce a pathology (disease) Van leeuwenhoek is the father of microbiology. Immunology: study of the body"s defense against infection. Microbiome: microbes in the tissues, skin, oral mucosa, and gi tract that cause no damage to the host organism. Pathogen: an organism that can induce a pathology (disease) or an infectious agent: extracellular: pathogen that can replicate outside the cell. Do not invade cells and proliferate in the extracellular environment. Some don"t even penetrate body tissues but adhere to epithelial surfaces and cause disease by secreting toxins.

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