11:067:300- Final Exam Guide - Comprehensive Notes for the exam ( 44 pages long!)

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Study guide: body temperature regulation (figure 22. 22) Thermoregulatory centers are located in the hypothalamus. Thermoreceptors are sensory neurons located peripherally in the skin and centrally in the anterior hypothalamus. monitor skin temperature and core body temperature, respectively, and send that information to the thermoregulatory center. Hypothalamic then compares input signals with desired temperature setpoint and coordinates an appropriate physiological response to raise or lower core temperature. Responses to increased temperature:heat loss from the body is promoted by dilation of blood vessels in the skin and by sweating. Heat lost through evaporative cooling sweat secretion sweat glands. Sympathetic cholinergic neurons cutaneous blood vessels vasodilation heat lost to environment. Responses to increased temperature: heat gain is generated by shivering and possibly by nonshivering thermogenesis. Shivering thermogenesis- body uses muscle contractions to generate heat. Signals from the hypothalamic thermoregulatory center initiate these skeletal muscle tremors. Vasoconstriction of blood vessels: precursors for thyroid hormone (fig 23. 4)

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