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01:146:329 Lecture Notes - Lecture 8: Leishmania Donovani, Leishmania, Chagas DiseaseExam


Department
Cell Biology and Neuroscience
Course Code
01:146:329
Professor
A.Keating
Study Guide
Final

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Lab 8: Trypanosoma and Leishmania (Both: Hemoflagellates)
Trypanosoma:
-Trypanosoma species and Leishmania species are members of the monophyletic protozoan
Class Kinetoplastida.
-They are commonly known as hemoflagellates because they are found in the blood or closely
associated tissues such as the spleen or liver of the human host.
-African trypanosomiasis, aka African Sleeping Sickness, is caused by two subspecies of
Trypanosoma brucei.
-American trypanosomiasis, aka Chagas’ disease, is caused by Trypanosoma cruzi.
Leishmania:
-In the genus Leishmania, there are a number of species that infect humans.
-Leishmania are responsible for three clinical manifestations: visceral, cutaneous, and
mucocutaneous leishmaniasis.
-There are four morphological forms that occur in the life cycles of the hemoflagellates, and not
all four forms occur in every species.
Responsible for identifying the organisms and the accompanying material:
A. Trypanosoma brucei rhodesiense
B. Trypanosoma brucei gambiense
C. Trypanosoma cruzi
D. Leishmania donovani
E. Glossina
F. Reduviids
General Morphology:
1. Draw and label the following forms:
Amastigote
Promastigote
Epimastigote
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