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Final

01:694:301 Study Guide - Final Guide: Glycosidic Bond, Phosphodiester Bond, Central Dogma Of Molecular BiologyExam


Department
Molecular Biology and Biochemistry
Course Code
01:694:301
Professor
F Deis
Study Guide
Final

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Quick-Assessment Review
BIO
Instructions
BIO
Go to : http://
This assessment is worth 30 points.
The classic experiment that demonstrated that radioactively labeled viral DNA
transforms bacterial cells was performed by
1.
(1 point)
Griffith.a.
Avery, MacLeod, and McCarty.b.
Kossel and Levene.c.
Hershey and Chase.d.
Watson and Crick.e.
According to the central dogma of molecular biology, genetic information flows in the
following direction:
2.
(1 point)
RNA Protein DNAa.
DNA RNA Proteinb.
DNA Protein RNAc.
Protein RNA DNAd.
None of the above are correct.e.
The DNA "backbone" is composed of3.
(1 point)
an amide bond between deoxyribose and a nitrogenous base.a.
a glycosidic bond between deoxyribose and a nitrogenous base.b.
a phosphodiester bond between the 3'- and 5'-hydroxyl groups of adjacentc.
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deoxyribose residues.
a phosphodiester bond between the 2'- and 5'-hydroxyl groups of adjacent
deoxyribose residues.
d.
None of the above are correct.e.
Nucleosomes are composed of all of the following except _______.4.
(1 point)
H1a.
H2b.
H3c.
H4d.
H5e.
There are approximately _____ human genes.5.
(1 point)
10,000a.
20,000b.
100,000c.
1,000,000d.
10,000,000e.
_____ are gene sequences that code for a gene product.6.
(1 point)
Intronsa.
Exonsb.
Nucleosomesc.
Cruciformsd.
Snurpse.
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The structure of H-DNA depends on7.
(1 point)
low pH.a.
Hoogsteen base pairing.b.
Watson-Crick base pairing.c.
Both A and B are correct.d.
All of the above are correct.e.
The number of times each DNA strand crosses the other is called the ________
number.
8.
(1 point)
writhinga.
supercoilingb.
splicingc.
cloningd.
linkinge.
When the L number of a circular DNA molecule decreases, the molecule's
conformation is said to be
9.
(1 point)
positively supercoiled.a.
negatively supercoiled.b.
a toroidal coil.c.
an interwound coil.d.
None of the above are correct.e.
The polyamines assist in the compression of eukaryotic chromosome structure
because they
10.
(1 point)
contain functional groups that bond to DNA.a.
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