CHEM 334- Final Exam Guide - Comprehensive Notes for the exam ( 98 pages long!)

• School: USC, SC, Carolina, South Carolina
• Department: Chemistry
• Course: CHEM 334
• Professor: George Handy

Document Summary

Intramolecular: nitrogen nucleophiles-weak; acid catalyst required, ammonia, primary amine, hydroxy amine, hydrazine, phenylhydrazine, oxygen nucleophiles- weak; acid catalyst required, ho h, r oh, michael addition, robinson annulation, retrosynthesis & forward synthesis for all above reactions. **will be updated after class on november 28** Concepts to know: aliphatic vs. aromatic amines vs. heterocyclic amines, primary, secondary and tertiary amines and amine salts, nomenclature of amines, be able to draw: Use lialh4/diethyl ether & water: synthesis done in class, mechanism for the imine formation, hofmann rearrangement mechanism, mechanism for alkylation of ammonia or amines, ammonia to primary amine, primary to secondary amine, secondary to tertiary amine. Concepts to know: reactions of amines, reaction with acid, this is from chem 333. All others are from previous exam material or chem: know how to use these reactions in synthesis, know how to use the synthesis of amines in synthesis. Purple= october 26; green= october 31; red=november 2; blue=november 7;