CHEM 35 Study Guide - Midterm Guide: Spectroscopy, Ketone, Thionyl Chloride

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Klein #62 65 in ch 6: choosing which side, charge, electronegativity, resonance d, hybridization (sp2 is more electronegative than sp2. Inductive: enolates, nitrogen could be part of enolate head, consider that there can be e or z enolates, this can form 2 different diastereomers (racemic) w, structure of enolate anion determines which diastereomeric product is favored c. d. Can have 2 different formations (e or z) leading to different diastereomers always 1,2 addition: aldol, grignard, n with double bond e. always 1,4 addition, micheal ii. cuprate, tlc, diastereomers present as 2 different spots b. Is a way to make negatively charged carbon compounds: another way is by cuprate, robinson, when you see micheal addition (1. 4 addition) think if. Esp with grignard reagent: when you see base as reagent, consider, base taking off acidic proton (not proton connected to double bond) esp for enolate, base attacking carbonyl carbon, base doing sn2 substitution e.