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BIMS 201 Study Guide - Midterm Guide: Paramesonephric Duct, Neural Tube Defect, Neural Crest

Biomedical Science
Course Code
BIMS 201
Elizabeth A.Crouch
Study Guide

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Exam 2 Review
Chapter 3b
What things become:
o Totipotent stem cells amnion and chorion
o Trophoblast placenta chorionic villus
o Interim kidney ducts Wolffian ducts in male repro. sys. and Mullerian ducts in
female repro. sys.
o Pharyngeal arches ear bones
4 ways stem cells are being used in research:
o drug discovery and dev.: stem cell cultures supply human cells affected in
particular disease
o growing stem cells in culture to observe earliest signs of disease
o creating tissues and organs for transplants, implants, and to study
o introducing reprogrammed proteins directly into body to stimulate stem cells
where they already are (iPS cells)
problems w/banking cord blood from newborns:
o very expensive and if baby has mutation, its own blood an’t e used to treat it
bc the blood will carry the mutated gene(s) as well
when have terminal illness, would have to do gene therapy on cells
before treating w/own cord blood
blastulation: implantation occurs INC levels of hCG hormone
o inner cell mass forms
o x-inactivation occurs
o want high levels of folic acid-prevents neural tube defects
o ectoderm nerve cells, neural crest cells, and epidermis
neural crest cells pigment cells, nerve sys., endocrine glands, CT, facial
o mesoderm notochord, somites, and dermis
somites muscle, skeleton, blood cells, excretory and repro. organs
o endoderm cells that line GI and resp. tracts and glandular cells in these sys.
Limit of viability: set by brain and resp. sys.
Know 1 drug, 1 nutrient, and 1 virus
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