BIOL 4376 Final: Pharmc exam 1

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29 Jul 2020
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Polymorphism- the higher the melting points the slower the absorption. Amorphous absorbed more quickly than crystalline zinc-insulin crystals. 5 microns and 20 nm to remove virus depyrogenation, sterilization, aseptic filling, lyophilization. Because they are resistant to moderate heating/steam sterilization. Dry heat, steam sterilization, filtration, irradiation, chemical sterilization. Advantages- removes particulates, cool process, good for thermally unstable. 128. filtration: how large of a micron filter is used in a iv set to remove particulates which may block pulmonary circulation. 129. filtration method dis/advantages? compounds, can be a continuous process. drug may bind to filter. 131. true or false filtration must be combined with aseptic filling: considerations of aseptic processing. Cons- hard to set up. whenever terminal sterilization is not possible or preferred. 136. dehydartion to produce an amorphous solid that is more convenient to handle and may be stored for a longer period of time.

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