BIOL 221 Study Guide - Final Guide: Integral Membrane Protein, Atp Synthase, Skeletal Muscle

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Electron transport coupled with chemiosmosis occurs in the mitochondria and produces 32 atp. Reduced electron carriers fadh2 and nadh[+h+] pass electrons to the electron transport chain. At three points when the electrons are passed from one integral membrane protein to the next, some energy is used to transport hydrogen ions into the space between the inner and outer membranes. The hydrogen ions can only pass back through atp synthase, which uses the energy to produce atp. Metabolic water is formed as hydrogen ions join with the reduced oxygen. Triglycerides are broken down by lipase into glycerol and fatty acids. Glycerol is converted into glyceraldehyde- 3-phosphate that is converted into pyruvate. Pyruvate enters the mitochondria, goes through the intermediate step to form acetyl-coa. Fatty acids are converted to acetyl-coa by beta oxidation. The acetyl-coa can enter the citric acid cycle or used to form ketone bodies (ketogenesis) that are burned aerobically by skeletal and cardiac muscle to produce atp.

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