NSCI 3300 Study Guide - Final Guide: Axon Hillock, Axon Terminal, Action Potential

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Below are general key concepts you should know for the cumulative portion of the final exam. This prevents toxins from entering the brain. Astrocytes in the capillaries are responsible for keeping contaminants from the bloodstream from entering the brain. Large and electrically charged molecules can"t exit the capillary on their own. One thing can can cross the blood-brain barrier is l-dopa. Synaptic transmission: how neurons communicate with each other, action potential arrives at presynaptic axon terminal, voltage-gated ca2+ channels open, ca2+ flows into axon terminal (due to depolarization. Influx of ca2+ causes synaptic vesicles containing the neurotransmitter to fuse with the presynaptic membrane: vesicles rupture via exocytosis, releasing neurotransmitters into the synaptic cleft, neurotransmitters bind to special receptor molecules in the postsynaptic membrane. Excitatory postsynaptic potential (epsp): depolarizes the postsynaptic neuron, increasing the probability of the postsynaptic neuron firing an action potential. Na+ channels opening, causing positive ions to flow in.