ES 342 Study Guide - Midterm Guide: Anterior Cerebral Artery, Middle Cerebral Artery, Internal Carotid Artery
Document Summary
Antibodies to presynaptic ca++ channels at terminal region of motor neuron. Muscles innervated by cranial nerves (bulbar m. ) show weakness. Proximal and distal limb muscles appear to be affected more than bulbar muscles. Cerebral blood flow: increase activation of brain= increase blood flow to area of increase neural activity. Cortical gray matter: bf 4-6 times more blood flow than cortical white mater. Gray matter cell bodies (metabolic center)= higher energy requirements. Blood flow from (l and r carotid arteries) and (vertebral basilar system) -> connect at circle of willis. Cerebral blood flow= 750- 1000 cc/ min = 50cc / gm of tissue co= 20% of resting valu. In any hemodynamic system, blood flow is directly proportional to the perfusion pressures and inversely proportional to the total resistance of the system. Cbf= (mean arterial pressure central venous p) / (cerebral vascular resistance.