MIC 301 Study Guide - Final Guide: Macrophage, White Blood Cell, Phagolysosome
18 Sep 2016
School
Department
Course
Professor
Document Summary
To recognize and defense against distinct invaders. Against portions of molecules the body recognizes as foreign. Specificity: 1 adaptive immune response 1 molecular shape; innate pamps, molecular shapes common to many microbes. Clonality: proliferation after induced of nearby cells (clones) Specific molecules the body recognizes as foreign. Recognition site: epitopes, three-dimensional, antigen determinants, part of antigens (shape, size and complexity) Exogenous antigen, endogenous antigen, autoantigen (immune cells that treat autoantigen as foreign are eliminated) Each b cell is covered with many bcr immunoglobin (differ between b cells) Y shape, top: antigen-binding site (variable regions) Specific of antibody immune response: binding between epitope and abs. The entire repertoire of an individuals" bcr can recognize many different epitopes. Secreted by b cells, have abs and antigen specificity to the bcr. Opsonization: opsonins stimulate phagocytosis (wbc phagocytize the ab and antigen attached) Agglutination: many ab aggregate antigens, make them phagocytized.
