MIC 301 Study Guide - Quiz Guide: Listeria Monocytogenes, Flaccid Paralysis, Neuromuscular Junction

• School: University at Buffalo
• Department: Microbiology And Immunology
• Course: MIC 301
• Professor: Amy Jacobs

Document Summary

Function of hemagglutinin prevents deactivation of neurotoxin by gastric enzymes and lowered ph of stomach. Toxin binds to receptor sites at neuromuscular junction ___________> blocks release of acetyl- choline (transmitter) _____________> prevents muscle contraction (flaccid paralysis) Neuromuscular symptoms first affect the muscles of the head blurred or double vision (diplopia) slurred speech (dysphonia) difficulty swallowing (dysphagia) Critical symptoms descending paralysis with involvement of respiratory system. Treatment polyvalent antitoxin therapy stomach lavage and enemas. Control/prevention adequate food preservation kill spores heat all canned food toxin inactivated at 80o c for 20 minutes. Mrs smith is a 62 year old housewife was admitted to the hospital with nausea and vomiting and abdominal cramps that have become severe. When asked from hospital staff then this started; mrs smith had difficulty speaking and was unable to respond. Mrs smith"s daughter who brought her in stated she was complaining of blurred vision and difficulty swallowing when they were having lunch.