PMY 302 Study Guide - Midterm Guide: Bronchoconstriction, Connecting Tubule, Asthma

• School: University at Buffalo
• Department: Pharmacology and Toxicology
• Course: PMY 302
• Professor: stewart Clark

Document Summary

Four bp categories, hypertension, normal: systolic <120mm hg, diastolic <80 mm hg, prehypertension: sys 120-139, dia 80-89, hypertension. Stage 2: sys >160, dia >100: types of hypertension (silent killer, primary/essential (most cases) Headache: drugs at on cardiac receptors, propranolol, non-selective beta blockers (1 heart and 2 - lungs, lower: resting and exercise hr, bp, co, renin, adverse effects. Exacerbation of asthma (bronchoconstriction: drugs at on vascular sm, verapamil and nifedipine. Used to lower bp and treat angina. Sinus bradycardia (verapamil, block hr, bad for heart failure) Reflex tachycardia (nifedipine, lower pr, increase co and hr: nitroprusside. Dilate both arteries and veins reduce left ventricle afterload and venous return (lower co) side effects. Metabolized to cyanide and thiocyanate hypertension crisis. Powerful drug through iv, short half-life: hydralazine. Side effects headache, angina pectoris, flushing, sinus tachycardia, palpitation, messed up hearbeat lower pr increase hr palpitation: drugs act on renal, thiazide diuretics, loop, short-term, high-ceiling, k+ sparing diuretics, drugs act on raas, captopril.