BSCI 105 Study Guide - Final Guide: Cyclic Adenosine Monophosphate, Conformational Change, Growth Factor

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The final exam will include a non-cumulative section based on the topical material covered at the end of the semester. This will be approximately 40 points worth of material. The remaining points will come from the cumulative section of the exam, assessing your retention of significant material from throughout the course: regulation of gene expression (campbell, chapter 18) The major mode of gene regulation is transcriptional regulation by transcription factors binding to regulatory dna. Prokaryotes use operons that are controlled by repressors, so both inducible and repressible operons are considered negative regulation. Eukaryotic genes use a combination of activators and repressors to control gene expression through upstream elements, but most genes are considered to be under positive control because they are off in the absence of transcription factors. In addition to the proximal promoter that recruits rna polymerase, there are more distal upstream elements that help determine the when, where, and how much of rna production.

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