BSCI 330 Study Guide - Midterm Guide: Lysosome, Cisterna, Nummelan Palloseura
9 Jan 2017
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Motor protein function - predict how defects in molecular motors or their effectors can affect mitotic spindle assembly, skeletal muscle contraction, or melanosome trafficking. Week 4 learning outcomes: describe how typical small gtpases function and are regulated. They are molecular switches controlling many different cell functions and are regulated by the binding of gdp or gtp and the hydrolysis of them. Gtpase gap(gtpase activator protein) facilitates hydrolysis of the gtp, such that it becomes gdp and is in its. Gdp-bound gtpase requires ran-gef (guanine exchange factor) to help kick off gdp and allow. Rangap doesn"t hydrolyze anything- they only facilitate hydrolysis by ran-gtp and ran-gdp. Rangef just exchanges the bitches: diagram the general pathway for nuclear import and export including the mechanism for how import and export receptors transport cargo into and out of the nucleus by recognizing a signal peptide.
