MATH 110 Midterm: Exam 1B Solutions Spring 2003

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14 Mar 2019
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You have a series of drugs sent to you by a colleague. All of them work at the neuromuscular junction to affect synaptic transmission between the muscle fiber and the motor neuron"s axon. Drug a reduces the epp by 10 mv at a concentration of 10 nm whereas drug b has the same 10 mv effect at 35 nm. And what is likely to be the ion channel(s) through which it exerts its effects: turns out the drug that reduces mepp frequency does not bind to a transmembrane receptor after all. It has to get access to the cytoplasmic side of the plasma membrane. 3 point extra credit question) you can use any toxin you know of test the conclusions you made in the answer to question #4. What you are looking for are toxins that do exactly what the two drugs do. What toxins would have the same effects as (and might work at the same sites as) drug.

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