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MIC 301 Study Guide - Spring 2018, Comprehensive Midterm Notes - Visceral Leishmaniasis, Virulence Factor, Virulence


Department
Microbiology and Immunology
Course Code
MIC 301
Professor
Williams Roger
Study Guide
Midterm

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MIC 301
MIDTERM EXAM
STUDY GUIDE
Fall 2018

Only pages 1-3 are available for preview. Some parts have been intentionally blurred.

Only pages 1-3 are available for preview. Some parts have been intentionally blurred.

Lecture 10:
Symbiosis- interaction between two different organisms living in close physical association,
most important in eukaryotes is the mitochondria
Parasitism- in order for the bacteria to survive the host must be harmed
Commensalism- by living in the host it can reproduce and grow, but the host goes unharmed
Mutualism- both the host and bacteria are able to benefit
Examples of parasitism: Vibrio Cholera
- Type: acute, possibly fatal
- Invasive: No
- Route: oral
- Toxigenic: yes
- Characteristic: dehydration
- Treatment: rehydration
- Attaches to the pilla and
destructs the host in order to
survive
Examples of parasitism: Mycobacterium tuberculosis
- Gram positive pathogen
- Type: chronic in most but asymptomatic, ⅓
of people have it, 10% of people develop
end stage disease (cholera is worse)
- Route: aerosol
- Toxigenic: No
- Treatment: antibiotics
Examples of parasitism: Chlamydia- obligate
intracellular pathogen
- Can cause problems with fertility if it goes into the
epithelial cells
- Two types: (type three secretion system)
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- EB: elementary body
- Protein synthesis, once in the cell it secretes it and turns to a raticular
body
- RB: raticular body
- Can turn back into EB after
Examples of commensalism: H Pylori- helical vectors
- Type: chronic, can lead to ulcer or cancer
- Invasive: minimally
- Route: Oral
- Toxigenic: No
- Characteristics: stays quiet, mechanism of dealing with stomach acidity
- Treatment: yes, antibiotic
- Can become parasitic if ulcer or cancer forms
Examples of mutualism and commensalism: Staph epidermidis
- Protects us from skin pathogens and inflammatory responses
Mutualist: mitochondria
- The mitochondria is a bacteria
Mitochondria vs Gram Negative
First Recognition of morphological similarity between mitochondria and bacteria
- Richard Altmann, Die Elementary Organismen, und ihre beziehungen zu den zellen in
[the cellular organelles and their relations to cells]
- Mitochondria is greek for mitos “thread” and chondrion “grain like”
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