MBIO 2815 Study Guide - Final Guide: Citric Acid Cycle, Facultative Anaerobic Organism, Fermented Milk Products

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Glycolysis is the oxidation of glucose to pyruvic acid, is usually the first stage of carbohydrate catabolism (breakdown of carbohydrate molecules to produce energy) The enzymes of glycolysis catalyze the splitting of glucose (a six carbon sugar) into two three-carbon sugars. These sugars are then oxidized, releasing energy, and their atoms are rearranged to form two molecules of pyruvic acid. During glycolysis, nad+ is reduced to nadh, and there is a net production of two atp molecules by substrate-level phosphorylation. The end product of glycolysis is pyruvic acid, which can be used by the cell to either undergo aerobic (respiration) or anaerobic (fermentation) process. There is also a net gain of two molecules of atp for each molecule of glucose that is oxidized and 2 nadh. Understand that there are alternative pathways to glycolysis that microorganisms may use to oxidize glucose. (ex. proteins / fat catabolism: compare and contrast aerobic vs anaerobic cycle.

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