NUR 3145- Midterm Exam Guide - Comprehensive Notes for the exam ( 71 pages long!)
Document Summary
Any chemical that can affect living processes: pharmacology. Study of drugs and their interactions with living systems: clinical pharmacology. Study of drugs in humans: therapeutics (pharmacotherapeutics) The use of drugs to diagnose, prevent, or treat disease or to prevent pregnancy. The ideal drug: effective, safe, selective, reversible, predictable, easy to administer, no interaction with other medications or food, low cost & easily accessible, stable, simple generic name, rapid, predictable response at relatively low dose, quickly eliminated by body. Determines how much of an administered dose gets to its sites of action: absorption, distribution, metabolism, excretion, pharmacodynamics. Determines the nature and intensity of the response: drug-receptor binding, functional state, placebo effects. Intensity of drug responses: individual variations: affects pharmacokinetics & pharmacodynamics! Genetics (pharmacogenomics: i. e. warfarin, succinylcholine, isoniazid, cytochrome p450, genetic testing. All prescription drugs must have some degree of effectiveness. Unapproved indications are unlabeled or off-label: classifications. Therapeutic usefulness: what is being treated by the drug, layman"s terms.
