LIFESCI 3 Study Guide - Final Guide: Allolactose, Inverse Relation, Signal Transduction
Document Summary
Eukaryotic transcription, 3 different rna polymerases used, rna pol. I: pre rrna (1) encodes rrna responsible for protein synthesis in the ribosome: rna pol. Ii: mrna, snrna, mirna (1) encodes rna involved in rna splicing, post-transcriptional control: rna pol. Iii: trna, 55 rrna (1) recognition particle for insertion of polypeptides into er: like prokaryotic transcription: uses 5" > 3" synthesis of amino acids, promoter dependent initiation, elongation, termination. Ii (a) recruited by activators (b) bridges pol. Ii and activators (c) promotes tfiih to phosphorylate tail (d) different subunits of mediator complex interact with different genes to speed transcription (i) med17 required for activation of all pol. Ii genes: following promoter escape rna pol. Ii sheds initiation factors and replaces them with elongation factors and rna processing enzymes (1) once mrna threads into exit channel capping enzymes are recruited > capping occurs before promoter escape only in rna pol.
