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Study Guide

[MCD BIO 165A] - Final Exam Guide - Everything you need to know! (48 pages long)


Department
Molecular, Cell, and Developmental Biology
Course Code
MCD BIO 165A
Professor
arispe
Study Guide
Final

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UCLA
MCD BIO 165A
FINAL EXAM
STUDY GUIDE

Only pages 1-3 are available for preview. Some parts have been intentionally blurred.

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Lecture'2
Plasma'membrane'varies'depending'on'temp'and'composition
-
Ogliosaccharides'are'bound'to'proteins'or'lipids'
Form'glycoprotein'and'glycolipids
-
sugars'only'present'on'the'outside'of'cell
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Outer'and'inner'lipids'are'very'different
-
Membrane'functions
Scaffold'for'exclusive'functions'
IE'chloroplast'w/'intergral'proteins'for'
photosynthesis
§
Integral'proteins'enable'exclusive'functions
§
Prevents'charged'and'large'molecules'to'enter/exit'easily'
Transports'solutes
Receptors'respond'to'external' signals
Interprets'environment
§
Uses'integral'proteins'to'receive'signals
§
Intracellular'interaction
Channels,'gap'junction
§
Enable'contact'between'two'cytoplasms'
§
Energy'transduction'
-
Enable'cells'to'sense'environment'and'migrate'
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Lecture'3
Interpret'signals'and'build'defenses
-
Cell'signaling'enables
Communication'between'cells
Organization'of'tissues/'morphogenesis
Integration'of'tissues'and'organs
-
Quiz%Notes%Midterm%1
Sunday,'September' 25,'2016
8:46'PM
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Ligand'->'receptor'->'signals
Key'and'lock
Phosphorylation'is'typical'in'signal'transduction
-
Every'kinase'has'a'phosphatase'
Allows'activation'and'deactivation
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Receptors'r'bound'to'cell' membrane
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Intracellular'molecules'interact/signal'receptors
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Changes'in'cell'shape/migration'as'result'of'ligand
Neural'outgrowth'
-
Autocrine'
Same'cell
Growth'factors
-
Paracrine
One'cell' makes'the'ligand'and'does'not'have'the'receptor
Cells'next'to'it'respond'to'ligand
Most'popular'way'of'signaling
-
Endocrine
Cells'are'far'away','requires'circulation
FSH'by'pituitary'at'base'of'brain'->'ovary'
-
G'protein'coupled'receptors
Require'another'group'of'proteins
Large'and'protein'has'to'go'7'times'thru'the'receptor'to'
be'assembled'
7'paths'receptor
GTP'bound'instead'of'GDP,'thus'changing'g'protein'group''
and'affecting'the'effector
-
Tyrosine'kinases
Are'enzymes
Tyrosine'phosphorlyation'bc'it'is'a'kinase
Monomer'becomes'dimer
Activate'across'each'other
§
-
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