ANSC 3272 Study Guide - Quiz Guide: Ventricular System, Peritoneum, Semipermeable Membrane
Document Summary
Considerations for drug delivery system choice: frequency. Quicker or more slowly absorbed from site of injection. + use alone or in conjunction with an infusion pump. + mucous membranes are highly vascularized fairly rapid onset. + not all chemical compounds can be administered via this route. + most recent development is an auto-infusion pump attached to a subcutaneous catheter. + designed to deliver a set volume over a set period: purpose, chemical nature of biology. Drug delivery systems: animal, equipment & facilities, expertise of personnel. Injection route of administration: how quickly do you want the drug to reach the desired concentration in the blood, rapidity of onset and decrease in concentrations is directly correlated with uptake into the general circulation. Ensure round-the-clock exposure to test agents at predictable levels. Permit continuous administration of short half-life proteins and peptides. Convenient method for chronic dosing of lab animals. Eliminate the need for nighttime or weekend dosing.
