BIOL 1107 Study Guide - Midterm Guide: Dna Repair, Pyrimidine Dimer, Dna Ligase

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30 Oct 2018
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Associated with sliding clamp only on the leading strand. Primase synthesizes short rna strand complementary to single-stranded dna. Ligase closes gap at 3" end of dna after excision repair. Okazaki fragments are synthesized using the lagging strand template from 5" to 3". Telomerase synthesizes dna in the 5" to 3" direction. *always adding nucleotides 5" to 3" but reading 3" to 5"* Rrna in ribosomes see cap and tail and know to start translation. A base-pair change is always a mutation. When eukaryotic dna lacks a cap and poly-a tail, translation occurs inefficiently. Desmosomes provide strong connections to resist pulling forces. Gap junctions allow communication between adjacent cells. Tight junctions form a watertight barrier between cells. When signal is transduced, physical form of signal changes between outside and inside of cell and signal. Cadherins (proteins) connect 2 cells with desmosomes, selective adhesion is amplified.