[MCB 2610] - Final Exam Guide - Comprehensive Notes for the exam (101 pages long!)

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Southern africa- high prevalence rates of hpv and stds (hiv) and tb lots of infectious diseases. Important message: were in peak age range for acquiring hpv (15-24 yrs) About the same cost spent for hiv treatments and care. 5 billion spent on health care a day . 3% Woman bear the grunt of symptoms of stds. Maturing of woman is important for pathogen bc as body changes affects environ that pathogen lives in. Might be ethic predispositions that make cultures more susceptible. Don"t have antiviral treatment for hpv at the time. Don"t cause tissue damage minimally cytopathic, doesn"t illicit big immflamatory response. Weak immune response that helps facilitates persistence. Life cycle: vast majority is transient (clear 1-2 yrs 90% of pop: similar time course as hiv. Virus needs to get down to basal cells which are the replicating cells. Hit and run- alters host genomics and leaves bc virus doesn"t need to be there anymore.

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