NURS 3664 Study Guide - Quiz Guide: Thrombolysis, Purkinje Fibers, Coronary Circulation
Exam 2 Review
• Flow of blood through heart
o Where, values, how oxygenated
• Systole and diastole
o Ventricular systole – contacting
o Diastole – filling
• Stroke volume
o SV = EDV – ESV
o How much blood heart is putting out with each beat
• Conduction system
o Where electric depolarization begins
o Purkinje fibers – most distal in depolarization
• Waveform
o Correlation electrically
o Action potential – absolute vs refractory
• Anything decreases pump or pressure will decrease coronary artery perfusion
o Not enough time spent in diastole, less oxygen perfused, heart functions less
• Modifiable and not modifiable risk factors for CAD
o Modifiable: smoking, HTN
o Non-modifiable: age, family history
• Angina
o Classic: responds to therapy
o Unstable: does not respond to therapy
• Drugs
o Nitroglycerin!!!!
▪ 5 minutes apart X 3
▪ take meds first with chest pain
▪ drug interactions – why?
o How impact HR and BP, ionotropic effect, contractility and rate
• Pos troponin leak – STEMI
• Until troponin leak – not positive MI
• Treatment
o Modify risk factors
o Time is muscle
o Limit complications
o Prevent reoccurrence
• Thrombolytic therapy
o Dissolve clot
o Time sensitive
• tPa
o complication: bleeding
o contraindications: absolute, relative
o what would limit someone from getting tPa
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