ADSC 3300 Study Guide - Quiz Guide: Malonyl-Coa, Pancreatic Lipase Family, Glucagon
25 Apr 2017
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Need to know about pathways: key enzymes, where it occurs, what starts with/ends with, and does it use or produce energy. **glucose-6-phosphate is a central compound to all the pathways we discussed. *glycolysis has 3 key enzymes (hexokinase/glucokinase, phosphofructokinase, pyruvate kinase) *gluconeogenesis has 4 key enzymes (pyruvate carboxylase, pep carboxykinase, f-1,6- phosphatase, glucose-6-phosphatase) Glucose to 2 pyruvate: aerobic glycolysis: glucose to 2 lactate: anaerobic glycolysis. Acetyl coa to palmitate: lipogenesis: or fatty acid to acetyl coa. Acetyl coa to 2 co2: kreb"s cycle aka citric acid cycle. Nadh to nad, oxygen to water: oxidative phosphorylation. *palmitate 8 acetyl coa 16 co2. 2 pathways needed for the complete oxidation of palmitate to stearate: beta-oxidation & citric acid cycle. Uncoupling oxidative phosphorylation is when heat is given off/lost as heat. Uncoupling proteins are increased by thyroid hormone, epinephrine, etc. 2 metabolic pathways needed to convert propionate to lactose: lactose synthesis & gluconeogenesis. *gluconeogenesis precursors: propionate, lactate, glycerol, and most amino acids.
