BIOLCHEM 415 Study Guide - Midterm Guide: Reactive Intermediate, Aspirin, Hyperbola

• School: U of M
• Department: Biological Chemistry
• Course: BIOLCHEM 415
• Professor: Aaron Goldstrohm

Document Summary

All amino acids are chiral, l-amino acids most common in proteins. D-amino acids used for other purposes like cell wall. Dopamine is what"s defective in people with parkinson"s disease. Gaba is transmitter and signaling molecule in pancreas. Pvit sdn for amino acids that aren"t good in alpha helix. Proteins starts folding up as its being made, as soon as it comes out of ribosome (secondary structure) Point of secondary structure is to maximize the hydrogen bonding. Alpha helix side chains on outside, angle towards n part. Also smushed like a spring stepped on, compact. Alpha helix 12 angstroms wide, about the length of dna major groove. Alpha helix can do hydrogen bonding with the top edges of bases, which are exposed in major grooves of dna. Helix-turn-helix has a lot of charged residues that makes hydrogen bonds with the bases to read the bases.