CHEM 210 Study Guide - Final Guide: Stage Name, Acid Dissociation Constant, Protic Solvent
Document Summary
Chem 210: structure and reactivity - lecture 12: energy diagrams. Kinetic variable: high humps = slow step. Rate determining step (rds): the step with the highest transition state. G step: end of step - beginning. Electrophiles: electron seeking atoms that have room to accept a pair of electrons. Nucleophiles: nucleus seeking atoms that have a pair of electrons to donate. Three factors to consider to see if a reaction is likely: Must be electron donor and acceptor present. The position of equilibrium between the reactants and products. The mechanism of the reaction, the details of the bond breaking and bond making that must take place to go from reactants to products. Bonds break and form at the same time for maximum stability. Leaving group: a stable species that can be detached from a molecule in a bond - breaking step. One sided attack of nucleophile inverts all three stereochemical bonds.
