BIO 325 Study Guide - Midterm Guide: Zygosity

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Autosomal
• Autosomal Recessive (skip generations, unaffected parents have affected offsprings,
consangous mating)
o Appears in both sexes with equal frequency
o Tends to skip generations
o Affected offsprings are born to unaffected parents
o When both parents are heterozygous (Aa x Aa), ÂĽ of offsprings will be affected
o When both parents are affected (rare), all offsprings will be affected
o Appears more frequently among families with consanguous mating
• Autosomal Dominant (does not skip generation, affected parents have affected
offsprings)
o Appears in both sexes with equal frequency
o Does not skip generations
o Both sexes transmit the trait to offspring
o Affected offspring must have an affected parent, unless posses a mutation
o When one parent is affected, heterozygous (Aa x AA), ½ of offspring will be
affected
o Unaffected parents do not transmit the trait
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