[GENETICS 633] - Midterm Exam Guide - Ultimate 15 pages long Study Guide!
Document Summary
Applications of population genetics: conserving wildlife, identifying and distinguishing individuals, reconstructing genealogical history, understanding the spread of infectious disease, identify genetic causes of trait variation. Heterozygote advantage: when the heterozygote in a population confers an evolutionary advantage and is selected for, even if the homozygote confers a disadvantage. Nucleotide diversity: the chance that, at any specific site, the bases of that site will differ from another member of the population. Humans have a nucleotide diversity of roughly 0. 1%, which is abnormally low: theories for why our species has such a low nucleotide diversity include population size, recent bottlenecks, and the relatively short time our species has existed. September 8, 2016 describing genetic variation; patterns of variation in natural populations. Large number of gametes: allele and genotype frequencies notation. Autosomal locus with two alleles, a1 and a2 p = freq of a1 q = freq of a2 p + q = 1.
