BSCI-1510 Study Guide - Midterm Guide: Retinoblastoma Protein, Euchromatin, Ribosomal Rna

• School: Vanderbilt University
• Department: Biological Sciences
• Course: BSCI-1510
• Professor: Singleton Charles

Document Summary

Genome: where all the genetic information is stored. Chromosomes: the physical entity that carries the genetic material. In e. coli: open reading frame, 4288 genes. almost all dna is devoted to genes. Genes vs. non-genetic information: structure, maintenance, regulation. Repeated sequences: transposons. not back to back. Number of genes is not much bigger. More than 90% of dna is not in the form of genes. Less than 10% is in the form of genes. The average size of a gene is 1000-2000 bp in archaea, and 10,000 to 100,000 in eukaryotes. Genes are not clustered based on function. 150 bp. histone octamer + h1 at entry and exit. Functions of histone tails: access to proteins, 30 nm fiber structure. Using hac and hdac to convert between 10 nm fiber (inaccessible) and 30 nm fiber (accessible) Cell cycle is a dependent sequence of events.