BIOL10004 Chapter Notes - Chapter 34: Hemoglobin, Anemia, Sickle-Cell Disease

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29 Jun 2018
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ESSENTIAL READING: EVOLUTION (Chapter 34: 833–839)
What is evolution?
Biological evolution is change over time in genetic composition of a population
Change in genetic structure within populations of same species leads to genetic differences
-> new species
Natural selection --> heritable traits improve survival or reproduction of an organism
Over time this trait will increase percentage of this trait because it is favourable
Alleles responsible for this trait increase in population at expense of other alleles
Natural selection
1. Excess reproduction - More individuals produce in the generation than the amount
that will survive
2. Genetic Variation - Individuals in population exhibit variation in traits. Variation is
generated by mutation, and vary between individuals of a population
3. Different genetic variants have different fitness - Fitter individuals will survive the
environment with the favourable trait but also produce fertile offspring. If an individual does
not produce offspring but survives, they do not contribute to the gene pool. Over time alleles
will change so that populations adapt to the environment because of the success of the
favourable traits
Evidence for Evolution
Spread of the weed Impatiens glandulifera
The weed was introduced to the Czech republic from the Himalayas in the 1890s
Slowly spread over habitat in 100 years
However when introduced into Slovakia 100 years later
Growth of the weed was exponential at 10x greater speed
This was due to the similar climate between Slovakia and Czech Republic
Plants in Czech Republic that better survived and reproduced
Therefore the dominant trait weeds would reproduce more adapted to the similar climate in
Slovakia
Artificial Selection
Domestication of animals
Animals were selectively bred by stockbreeders
Artificial selection produces a wide variety of shapes in domestic animals
Choosing to allow certain extreme types to reproduce while others are prevented from
reproducing
Insecticide resistance
Insecticides applied to kill flies and mosquitoes
Insects can break down the poison and survive to reproduce
Certain individuals possess the resistance allele of a gene encoding esterase enzyme
Individuals that carry this allele breaks down poisons and reproduce
Increases offspring with this allele
Over time the population of insects will have an insecticide resistance genetic makeup
Eventually pesticide will be useless against the immune pest population
Natural selection in humans
Seen in humans
Genetic variants increase or decrease individual lifespans
Worse of better at surviving and reproducing
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Document Summary

Biological evolution is change over time in genetic composition of a population. Change in genetic structure within populations of same species leads to genetic differences. Natural selection --> heritable traits improve survival or reproduction of an organism. Over time this trait will increase percentage of this trait because it is favourable. Alleles responsible for this trait increase in population at expense of other alleles. Excess reproduction - more individuals produce in the generation than the amount. Genetic variation - individuals in population exhibit variation in traits. 2. generated by mutation, and vary between individuals of a population. Different genetic variants have different fitness - fitter individuals will survive the environment with the favourable trait but also produce fertile offspring. If an individual does not produce offspring but survives, they do not contribute to the gene pool. Over time alleles will change so that populations adapt to the environment because of the success of the favourable traits.

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