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Chapter 4

SCIE 1P50 Chapter Notes - Chapter 4: Apopka, Florida, Animal Testing, Environment And Climate Change Canada

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Caroline Starrs

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Class #8! Science & Society! September. 30, 2011
English-Wabigoon River System
- River system located in northwestern Ontario
- Contaminated by wastewater from pulp and paper company
- 9000 kilograms of mercury dumped into river between 1962 and 1970 (guesstimate)
- Known as one the most mercury-contaminated freshwater system in the world
- 1970, Ontario government ordered a stop to mercury dumping
- Consider the long term damage (neurological, developmental, speech problems and
horrific side effects among children)
- Minamata Disease
Endocrine Disrupters
- PCB’s, dioxins, mercury, etc.
- Interfere with body’s hormones
- Alter reproductive development
- Lake Apopka, Florida
- 1980 chemical spill
- Alligator eggs have high mortality rate
Endocrine Disrupters & Humans
- Increasing rates of:
- Reproductive disorders
- Infertility
- Some Cancers
- Environment Canada has made EDS research a top priority
- Lack of human studies
Determining Health Effects of Pollutants
- Dose: amount that enters the body
- Response: type & amount of damage
- Lethal dose
Determining Toxicity
- Lethal dose - 50%
- Dose that is lethal to 50% of the population
- Determined for all new synthetic chemicals
- Animal testing
- Effective dose - 50%
- ED50
- Dose that causes 50% of population to exhibit specific response
- Animal testing
Dose-Response Curve
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