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Carleton University
PSYC 2800
Amanda Helleman

Next lecture 11bw12 The Frontal Lobe and ShortTerm MemoryAll sensory systems project to the frontal lobesThere are a lot of inputs going into the frontal lobe but little coming out of lobe Location of workingmemory During tasks in which monkeys must keep information inshortterm memory over a delay certain cells in thefrontalcortex will fire throughout the delayAnimals that have not learned the task show nosuch cell activityDelayed response taskDelayedalternation taskDelayedmatchingtosample taskIf we do single cell recording where were actually measuringthe firing of the cells in the frontal lobe what happens is that we get very specific cells that fire throughout the delayed period It is almost like these cells are saying it is in the left it is in the left it is in the left or its the green one its the green on its the green oneanimals that have not learned this task show no cell activity when presented with it initially Reciprocal Connections for Explicit MemoryThe neocortex projects to the entorhinal cortex which projects back to the neocortexBenefitsSignals from the medial temporal regions back to the cortical sensory regions keep the sensory experience alive in the brain the idea that the neural record outlasts the experience So you may walk by someone hello you have their face and their name that person leaves but your frontal lobe and cortical regions are keeping that person alive in your memoryPathway back to the neocortex means it is kept apprised of the information being processed in medial temporal regions Korsakoffs Syndrome explicit memory remember diagramIndirect cause of chronic alcohol consumption direct cause of malnutritionAlcohol is not what is killing off the brain cells it is malnutritionPoor diet Lack of vitamin B1 thiamine Without a good varied diet you will lack critical vitamins like vitamin B1 we require it for normal neuronal processing we dont make it in our bodyChronic alcoholism compromises thiamine absorption from GI tract impairs thiamine storageMay also result from dietary deficiencies prolonged vomiting or eating disordersResults in permanent loss of ability to learn new information anterograde amnesia and retrieve old information retrograde amnesia
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